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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM145
All Species:
18.18
Human Site:
S131
Identified Species:
40
UniProt:
Q8NBT3
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NBT3
NP_775904.2
493
55604
S131
E
E
G
T
R
Y
L
S
C
S
S
G
R
S
F
Chimpanzee
Pan troglodytes
XP_001142679
487
54558
S125
E
E
G
T
R
Y
L
S
C
S
S
G
R
S
F
Rhesus Macaque
Macaca mulatta
XP_001097777
479
53690
S117
E
E
G
T
R
Y
L
S
C
S
S
G
R
S
F
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8C4U2
746
82455
S131
E
E
G
T
R
Y
L
S
C
S
S
G
R
S
F
Rat
Rattus norvegicus
XP_002725596
493
55754
S131
E
E
G
T
R
Y
L
S
C
S
S
G
R
S
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517646
125
14239
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5U239
547
61735
W138
F
R
S
V
R
E
R
W
W
Y
I
A
L
S
K
Zebra Danio
Brachydanio rerio
XP_686062
369
41174
F39
L
H
T
T
Y
K
M
F
M
T
A
A
G
V
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120120
421
48474
F91
I
P
L
S
T
V
T
F
E
E
S
G
C
I
E
Nematode Worm
Caenorhab. elegans
NP_510017
513
59248
D163
C
D
P
S
E
S
E
D
R
R
L
Y
N
N
E
Sea Urchin
Strong. purpuratus
XP_001200832
438
49887
Q108
I
S
N
C
N
A
G
Q
L
T
M
T
N
G
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.3
92.4
N.A.
N.A.
64
96.5
N.A.
24.3
N.A.
68.5
49.7
N.A.
N.A.
30.4
29.2
35.5
Protein Similarity:
100
94.1
93.7
N.A.
N.A.
64.6
97.5
N.A.
24.7
N.A.
75.1
55.7
N.A.
N.A.
46.8
49.1
50.9
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
0
N.A.
13.3
6.6
N.A.
N.A.
13.3
0
0
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
0
N.A.
13.3
26.6
N.A.
N.A.
20
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
0
0
0
10
19
0
0
0
% A
% Cys:
10
0
0
10
0
0
0
0
46
0
0
0
10
0
0
% C
% Asp:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% D
% Glu:
46
46
0
0
10
10
10
0
10
10
0
0
0
0
28
% E
% Phe:
10
0
0
0
0
0
0
19
0
0
0
0
0
0
46
% F
% Gly:
0
0
46
0
0
0
10
0
0
0
0
55
10
10
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
19
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% I
% Lys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
19
% K
% Leu:
10
0
10
0
0
0
46
0
10
0
10
0
10
0
0
% L
% Met:
0
0
0
0
0
0
10
0
10
0
10
0
0
0
0
% M
% Asn:
0
0
10
0
10
0
0
0
0
0
0
0
19
10
0
% N
% Pro:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
55
0
10
0
10
10
0
0
46
0
0
% R
% Ser:
0
10
10
19
0
10
0
46
0
46
55
0
0
55
0
% S
% Thr:
0
0
10
55
10
0
10
0
0
19
0
10
0
0
0
% T
% Val:
0
0
0
10
0
10
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
46
0
0
0
10
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _